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AAV vectors

Showing 1 - 25 of 208

STUDY
CONDITIONS
INTERVENTIONS
LOCATIONS

Seroprevalence and Seroconversion of Antibodies to

Recruiting
  • Hemophilia A
  • Blood sample collection
  • Madison, Wisconsin
    Covance Inc
Sep 16, 2022

Alpha 1-Antitrypsin Deficiency Trial in Gainesville, Worcester (rAAV2-CB-hAAT Gene Vector)

Completed
  • Alpha 1-Antitrypsin Deficiency
  • rAAV2-CB-hAAT Gene Vector
  • Gainesville, Florida
  • +1 more
Apr 8, 2020

Study in Subjects Who Received vMCO-I Administered Via

Enrolling by invitation
  • Retinitis Pigmentosa
  • +2 more
  • Gene Therapy product:vMCO-I
  • Cuttack, Odisha, India
    JPM Rotary Club of Cuttack Eye Hospital and Research Institute
Jun 26, 2023

Liver Biopsy In Haemophilia Gene Therapy

Not yet recruiting
  • Hemophilia B, Severe
  • Hemophilia A, Severe
    • (no location specified)
    Mar 23, 2021

    Parkinson's Disease Trial run by the National Institute of Neurological Disorders and Stroke (NINDS) (Convection enhanced

    Completed
    • Parkinson's Disease
    • Convection enhanced delivery/AAV2-GDNF
    • Bethesda, Maryland
      National Institutes of Health Clinical Center
    Jan 26, 2023

    Retinitis Pigmentosa, Retinitis, Retinal Diseases Trial in Puerto Rico, United States (Gene Therapy Product-vMCO-010, Sham

    Active, not recruiting
    • Retinitis Pigmentosa
    • +6 more
    • Gene Therapy Product-vMCO-010
    • Sham Injection
    • Beverly Hills, California
    • +6 more
    Jul 13, 2022

    Squamous Cell Head Neck Cancer, Radiation Induced Xerostomia, Salivary Hypofunction Trial run by the (AAV2hAQP1)

    Recruiting
    • Squamous Cell Head and Neck Cancer
    • +2 more
    • AAV2hAQP1
    • Bethesda, Maryland
      National Institutes of Health Clinical Center, 9000 Rockville Pi
    May 3, 2022

    Non-syndromic Retinitis Pigmentosa Trial in Pittsburgh, Paris, London (Gene therapy: GS030-DP AND Medical device: GS030-MD)

    Recruiting
    • Non-syndromic Retinitis Pigmentosa
    • Gene therapy: GS030-DP AND Medical device: GS030-MD
    • Pittsburgh, Pennsylvania
    • +2 more
    Jul 25, 2022

    Hypertriglyceridemia, Familial Trial in Nanjing (GC304)

    Not yet recruiting
    • Hypertriglyceridemia, Familial
    • GC304
    • Nanjing, China
      Affiliated Jinling Hospital, Medical School, Nanjing University
    May 5, 2023

    Hemophilia B Trial in Washington (SB-FIX)

    Terminated
    • Hemophilia B
    • SB-FIX
    • Washington, District of Columbia
      Georgetown University Medical Center
    Mar 8, 2022

    Bietti's Crystalline Dystrophy Trial in China (ZVS101e)

    Recruiting
    • Bietti's Crystalline Dystrophy
    • Beijing, Beijing, China
    • +3 more
    Apr 16, 2023

    Pompe Disease Trial in Gainesville (genetic, drug, other)

    Completed
    • Pompe Disease
    • Recombinant Adeno-Associated Virus Acid Alpha-Glucosidase
    • +7 more
    • Gainesville, Florida
      Clinical and Translational Research Building (CTRB), University
    Mar 24, 2022

    Pompe Disease (Late-onset) Trial (No Intervention)

    Not yet recruiting
    • Pompe Disease (Late-onset)
    • No Intervention
    • (no location specified)
    Nov 21, 2023

    Leber Hereditary Optic Neuropathy Trial in Worldwide (GS010, Placebo)

    Active, not recruiting
    • Leber Hereditary Optic Neuropathy
    • GS010
    • Placebo
    • Pasadena, California
    • +12 more
    Aug 2, 2022

    MPS I Trial in Oakland (SB-318)

    Terminated
    • MPS I
    • SB-318
    • Oakland, California
      UCSF Benioff Children's Hospital Oakland
    Jan 6, 2023

    Leber Hereditary Optic Neuropathy Trial in Worldwide (GS010, Sham)

    Completed
    • Leber Hereditary Optic Neuropathy
    • GS010
    • Sham
    • Pasadena, California
    • +6 more
    Jul 25, 2022

    Liver Biopsy Following Gene Therapy For Hemophilia

    Not yet recruiting
    • Hemophilia A
    • Hemophilia B
    • Liver Biopsy
    • Memphis, Tennessee
      St. Jude Children's Research Hospital
    Jun 27, 2023

    AADC Deficiency Trial in San Francisco, Columbus (AAV2-hAADC)

    Recruiting
    • AADC Deficiency
    • San Francisco, California
    • +2 more
    Jan 14, 2022

    Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis, End Stage Renal Disease Trial in France (Discontinuation (or not

    Recruiting
    • Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis
    • End Stage Renal Disease
    • Discontinuation (or not initiation) of Immunosuppressive Therapy
    • Maintenance (or initiation) of immunosuppressive treatment: Imurel®, Mabthera®,Cellcept®, Cortancyl®
    • Amiens, France
    • +54 more
    Jan 6, 2023

    LTFU for Gene Transfer Subjects With Hemophilia B

    Completed
    • Hemophilia B
      • Philadelphia, Pennsylvania
      • +1 more
      May 14, 2020

      Leber Hereditary Optic Neuropathy (Optic, Atrophy, Hereditary, Leber) Trial (GS010)

      Available
      • Leber Hereditary Optic Neuropathy (Optic, Atrophy, Hereditary, Leber)
      • GS010
      • (no location specified)
      Aug 2, 2021

      Bietti's Crystalline Dystrophy Trial in Beijing (ZVS101e)

      Recruiting
      • Bietti's Crystalline Dystrophy
      • Beijing, Beijing, China
        Peking University Third Hospital
      Feb 2, 2023

      Avacostar - (PASS)

      Not yet recruiting
      • ANCA-associated Vasculitis
        • (no location specified)
        Jun 12, 2023

        Antineutrophil Cytoplasmic Antibody-associated Vasculitis Trial (Avacopan, Placebo, Standard of Care)

        Not yet recruiting
        • Antineutrophil Cytoplasmic Antibody-associated Vasculitis
        • (no location specified)
        Oct 6, 2023

        Retinitis Pigmentosa, Retinal Diseases, Retinal Degeneration Trial in Cuttack (Gene Therapy product:vMCO-I)

        Completed
        • Retinitis Pigmentosa
        • +2 more
        • Gene Therapy product:vMCO-I
        • Cuttack, Odisha, India
          JPM Rotary Club of Cuttack Eye Hospital and Research Institute
        Jun 2, 2021